A first case of Mixta calida bacteremia and meningitis in a 5-week old child

Infect Dis (Lond). 2024 Nov;56(11):1000-1002. doi: 10.1080/23744235.2024.2391022. Epub 2024 Aug 15.

Abstract

Mixta calida, previously known as Pantoea calida, was initially isolated from powdered infant milk in 2010. It falls within the Erwiniaceae family (class: Enterobacterales). While Mixta calida was traditionally regarded as non-pathogenic, we now present a case of Mixta calida bacteraemia and meningitis in a 5-week-old child, successfully treated with cefotaxime. This case, in contrast to prior reports with potential contamination issues, is the first to offer compelling evidence of Mixta calida's pathogenicity in humans.

Keywords: Mixta calida meningitis; bacteremia; pathogenicity.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents* / therapeutic use
  • Bacteremia* / drug therapy
  • Bacteremia* / microbiology
  • Cefotaxime / therapeutic use
  • Enterobacteriaceae Infections* / diagnosis
  • Enterobacteriaceae Infections* / drug therapy
  • Enterobacteriaceae Infections* / microbiology
  • Gammaproteobacteria / pathogenicity
  • Humans
  • Infant
  • Meningitis, Bacterial / diagnosis
  • Meningitis, Bacterial / drug therapy
  • Meningitis, Bacterial / microbiology
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Cefotaxime

Supplementary concepts

  • Mixta calida