Ceftriaxone-resistant Salmonella enterica serovar Newport: a case report from South India

Front Public Health. 2024 Aug 8:12:1418221. doi: 10.3389/fpubh.2024.1418221. eCollection 2024.

Abstract

Salmonella enterica serovar Newport is a human pathogen underreported in most developing countries. It is known for causing gastroenteritis and extraintestinal infections. In this case report, we report the case of ceftriaxone-resistant Salmonella enterica serovar Newport from South India, causing acute gastroenteritis in a sixty-year-old female patient having a history of antimicrobial therapy and recent hospital admission. Serovar Newport, especially among antibiotic-exposed patients, poses a significant public health threat due to its ability to acquire multidrug resistance. This emphasizes the necessity for robust surveillance and monitoring of nontyphoidal Salmonella infections, particularly given the limited data on serovar Newport in India. Vigilance in clinical practice and public health initiatives is crucial to effectively address the emergence and spread of multidrug-resistant strains.

Keywords: Salmonella Newport; ceftriaxone resistance; ceftriaxone resistant non-typhoidal Salmonella; gastroenteritis; septic shock.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents* / pharmacology
  • Anti-Bacterial Agents* / therapeutic use
  • Ceftriaxone* / pharmacology
  • Ceftriaxone* / therapeutic use
  • Drug Resistance, Multiple, Bacterial
  • Female
  • Gastroenteritis / drug therapy
  • Gastroenteritis / microbiology
  • Humans
  • India
  • Microbial Sensitivity Tests
  • Middle Aged
  • Salmonella Infections* / drug therapy
  • Salmonella Infections* / microbiology
  • Salmonella enterica* / drug effects
  • Salmonella enterica* / isolation & purification
  • Serogroup

Substances

  • Ceftriaxone
  • Anti-Bacterial Agents

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by JSS AHER, Mysuru.