Genetics and Genomics 101

Vet Clin North Am Food Anim Pract. 2024 Nov;40(3):345-355. doi: 10.1016/j.cvfa.2024.05.001. Epub 2024 Aug 23.

Abstract

Genetic mutations, both favorable and unfavorable, are the raw material for improvement in livestock populations. The random inheritance of these mutations is essential for generating progenies with genetic potential greater than their parents. These mutations can act either in a simple manner, such that a single alteration disrupts phenotype, or in a complex manner where hundreds or thousands of mutations of small effect create a continuous distribution of phenotypes. Selection tools leverage phenotypic records, pedigrees, and genomics to estimate the genetic potential of individual animals. This more accurate accounting of genetic potential has generated enormous gains in livestock populations.

Keywords: Breeding; Cattle; Complex traits; DNA; Genomics; Genotype.

Publication types

  • Review

MeSH terms

  • Animals
  • Breeding
  • Genomics*
  • Livestock* / genetics
  • Mutation
  • Pedigree
  • Phenotype