Abstract
Lymphoid cells from bone marrow radiation chimeras do not produce normal levels of IL 2 but are capable of responding to IL 2 in mitogenic and cytotoxic assays in vitro. The administration of recombinant human IL 2 into host mice that have received allogeneic, H-2-compatible marrow did not enhance mortality.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Bone Marrow Transplantation*
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Cell Line
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Cytotoxicity, Immunologic
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Disease Models, Animal
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Interleukin-2 / biosynthesis*
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Interleukin-2 / physiology
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Lymphocyte Activation
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Male
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Mast-Cell Sarcoma / immunology
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Mice
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Mice, Inbred C3H
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Mice, Inbred CBA
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Mice, Inbred DBA
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Postoperative Complications
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Spleen / cytology
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T-Lymphocytes, Cytotoxic / immunology