Remote Hepatocellular Carcinoma Recurrence to Lumbar Spine Post Orthotopic Liver Transplantation-A Report of Two Cases and a Review of the Literature

Matthew T Newman; Rasham Mittal; Dean La Barba; Amandeep Sahota

doi:10.1016/j.transproceed.2024.08.017

Remote Hepatocellular Carcinoma Recurrence to Lumbar Spine Post Orthotopic Liver Transplantation-A Report of Two Cases and a Review of the Literature

Transplant Proc. 2024 Sep;56(7):1613-1616. doi: 10.1016/j.transproceed.2024.08.017. Epub 2024 Aug 26.

Authors

Matthew T Newman¹, Rasham Mittal², Dean La Barba³, Amandeep Sahota²

Affiliations

¹ Department of Internal Medicine, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California. Electronic address: [email protected].
² Department of Gastroenterology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California; Department of Transplant Hepatology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California.
³ Department of Gastroenterology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California.

PMID: 39191548
DOI: 10.1016/j.transproceed.2024.08.017

Abstract

Late recurrence of hepatocellular carcinoma (HCC) following orthotopic liver transplant (OLT) is infrequently reported, and among cases, those isolated to the spine are rare. Prognoses are poor for this patient population, and no work has been undertaken to create uniform guidelines for management. Here, we report two cases of late recurrent HCC to the spine after OLT and favorable survival outcomes following intervention.

Publication types

Case Reports
Review

MeSH terms

Carcinoma, Hepatocellular* / surgery
Humans
Liver Neoplasms* / surgery
Liver Transplantation*
Lumbar Vertebrae / surgery
Male
Middle Aged
Neoplasm Recurrence, Local*
Spinal Neoplasms / secondary
Spinal Neoplasms / surgery