Assessment of Salt, Potassium, and Iodine Intake in the Croatian Adult Population Using 24 h Urinary Collection: The EH-UH 2 Study

Nutrients. 2024 Aug 7;16(16):2599. doi: 10.3390/nu16162599.

Abstract

Cardiovascular diseases, which are the leading cause of death in Croatia, are linked to the high prevalence of hypertension. Both are associated with high salt intake, which was determined almost two decades ago when Croatian Action on Salt and Health (CRASH) was launched. The main objective of the present study was to evaluate salt, potassium, and iodine intake using a single 24 h urine sample in a random sample of the adult Croatian population and to analyse trends in salt consumption after the CRASH was intensively started.

Methods: In this study, we analysed data on 1067 adult participants (mean age 57.12 (SD 13.9), men 35%).

Results: Mean salt and potassium intakes were 8.6 g/day (IQR 6.2-11.2) and 2.8 g/day (IQR 2.1-3.5), respectively, with a sodium-to-potassium ratio of 2.6 (IQR 1.8-3.3). We detected a decrease of 17.6% (2 g/day less) in salt consumption compared with our previous salt-mapping study. However, only 13.7% and 8.9% met the WHO salt and potassium recommended targets of 5 g/day and 3.5 g/day, respectively. Salt intake was higher, and potassium ingestion was lower, in rural vs. urban regions and in continental vs. Mediterranean parts of Croatia. Moderate to severe iodine insufficiency was determined in only 3% of the adult participants.

Conclusion: In the last fifteen years, salt consumption has been significantly reduced in the Croatian adult population because of the intensive and broad CRASH program. However, salt intake is still too high, and potassium ingestion is too low. Salt reduction programs are the most cost-effective methods of cardiovascular disease prevention and merit greater consideration by the government and health policy makers.

Keywords: 24 h urine; iodine; population-based study; potassium; salt; sodium.

MeSH terms

  • Adult
  • Aged
  • Croatia / epidemiology
  • Female
  • Humans
  • Hypertension / epidemiology
  • Iodine* / administration & dosage
  • Iodine* / deficiency
  • Iodine* / urine
  • Male
  • Middle Aged
  • Potassium / urine
  • Potassium, Dietary* / administration & dosage
  • Potassium, Dietary* / urine
  • Sodium Chloride, Dietary* / administration & dosage
  • Urine Specimen Collection / methods

Substances

  • Sodium Chloride, Dietary
  • Iodine
  • Potassium, Dietary
  • Potassium

Grants and funding

This study was funded by a Croatian Science Foundation research grant (IP-06-2016), which supported the project Epidemiology of hypertension and salt intake in Croatia (EH—UH 2); unrestricted research grants from the Croatian Society of Hypertension and the Croatian Hypertension League; the Croatian Science Foundation program “Young Researchers’ Career Development Project—training of doctoral students”, which funded the work of Mihaela Marinović Glavić (PhD student), DOK-2018-09; and financial and organization help from the School of Medicine University of Zagreb and the Croatian Institute of Public Health.