Clinical and hematological findings in alpacas (Vicugna pacos) with and without Candidatus Mycoplasma haemolamae infection

Sci Rep. 2024 Aug 30;14(1):20152. doi: 10.1038/s41598-024-70956-9.

Abstract

Anemia is a common problem in South American camelids (SACs). Infections with Candidatus Mycoplasma haemolamae (CMh), a cell-wall free, hemotropic bacterium, are often suspected to be an important cause of anemia, as the pathogen infects the erythrocytes and is found in the blood of up to 30% of SACs. The information on the clinical signs of animals infected with this pathogen vary widely. Most infections are clinically inapparent. Treatment is usually carried out with oxytetracycline. A detailed overview of the clinical and hematological findings in 13 alpacas infected with Candidatus M. haemolamae (CMh+), based on patients from our university clinic and comparing those findings with the results of 22 negative alpacas (CMh-) is provided. Assignment to both groups was based on the PCR result. No relevant clinical or hematological differences between CMh+ and CMh- were found, the clinical signs in CMh+ were usually due to comorbidities. The examination of a blood smear alone proved to be insufficient; a PCR test should be carried out to confirm or rule out an infection. A critical review of the need for antibiotic treatment on the basis of a positive test result alone is recommended.

Keywords: Anemia; Blood smear; Clinical findings; Hemotropic mycoplasma; South American camelids.

MeSH terms

  • Anemia / blood
  • Anemia / microbiology
  • Anemia / veterinary
  • Animals
  • Anti-Bacterial Agents / therapeutic use
  • Camelids, New World* / microbiology
  • Female
  • Male
  • Mycoplasma Infections* / blood
  • Mycoplasma Infections* / diagnosis
  • Mycoplasma Infections* / drug therapy
  • Mycoplasma Infections* / microbiology
  • Mycoplasma Infections* / veterinary
  • Mycoplasma* / genetics
  • Mycoplasma* / isolation & purification
  • Oxytetracycline / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Oxytetracycline