[Virtual reality-brain computer interface hand function enhancement rehabilitation system incorporating multi-sensory stimulation]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2024 Aug 25;41(4):656-663. doi: 10.7507/1001-5515.202312055.
[Article in Chinese]

Abstract

Stroke is an acute cerebrovascular disease in which sudden interruption of blood supply to the brain or rupture of cerebral blood vessels cause damage to brain cells and consequently impair the patient's motor and cognitive abilities. A novel rehabilitation training model integrating brain-computer interface (BCI) and virtual reality (VR) not only promotes the functional activation of brain networks, but also provides immersive and interesting contextual feedback for patients. In this paper, we designed a hand rehabilitation training system integrating multi-sensory stimulation feedback, BCI and VR, which guides patients' motor imaginations through the tasks of the virtual scene, acquires patients' motor intentions, and then carries out human-computer interactions under the virtual scene. At the same time, haptic feedback is incorporated to further increase the patients' proprioceptive sensations, so as to realize the hand function rehabilitation training based on the multi-sensory stimulation feedback of vision, hearing, and haptic senses. In this study, we compared and analyzed the differences in power spectral density of different frequency bands within the EEG signal data before and after the incorporation of haptic feedback, and found that the motor brain area was significantly activated after the incorporation of haptic feedback, and the power spectral density of the motor brain area was significantly increased in the high gamma frequency band. The results of this study indicate that the rehabilitation training of patients with the VR-BCI hand function enhancement rehabilitation system incorporating multi-sensory stimulation can accelerate the two-way facilitation of sensory and motor conduction pathways, thus accelerating the rehabilitation process.

脑卒中(stroke)是由于脑部血液供应突然中断或脑血管破裂,导致脑细胞损伤进而损害患者运动和认知能力的一种急性脑血管疾病。融合脑—机接口(BCI)和虚拟现实(VR)的新型康复训练模式,不仅能促进脑网络功能激活,而且能为患者提供沉浸感强、趣味性强的情境反馈。本文设计了融合多感官刺激反馈、BCI和VR的手部康复训练系统,通过虚拟场景的任务引导患者运动想象,获取患者运动意图,进而在虚拟场景下进行人机交互;同时,融入触觉反馈进一步增加患者本体感受,从而实现基于视、听、触觉多感官刺激反馈的手功能康复训练。本研究通过对比分析加入触觉反馈前后的脑电信号数据内不同频段功率谱密度的差异,发现加入触觉反馈后运动脑区被明显激活,运动脑区的功率谱密度在高γ频段有显著提升。研究结果说明,患者在融合多感官刺激的VR—BCI手功能增强康复系统中进行康复训练,能够加速感觉传导通路和运动传导通路的双向促通,从而加速康复进程。.

Keywords: Brain-computer interface; Hand functional rehabilitation; Haptic feedback; Multi-sensory stimulation feedback; Virtual reality.

Publication types

  • English Abstract

MeSH terms

  • Brain-Computer Interfaces*
  • Electroencephalography*
  • Feedback, Sensory
  • Hand* / physiology
  • Humans
  • Motor Cortex / physiology
  • Stroke Rehabilitation* / instrumentation
  • Stroke Rehabilitation* / methods
  • User-Computer Interface
  • Virtual Reality*

Grants and funding

国家自然科学基金资助项目(U20A20192);河北省自然科学基金资助项目(F2022203079);河北省创新能力提升计划项目(22567619H)