Renal Dysfunction in a Patient With Crohn's Disease During Ustekinumab Treatment: A Case Report and Review of the Literature

Curr Ther Res Clin Exp. 2024 Jul 5:101:100753. doi: 10.1016/j.curtheres.2024.100753. eCollection 2024.

Abstract

Ustekinumab is a first-line drug for Crohn's disease. However, little is known about its potential adverse effects on renal function. We present the case of a 42-year-old man with Crohn's disease who developed chronic renal dysfunction during ustekinumab treatment, which resolved after discontinuing ustekinumab. The findings underscore the importance of close monitoring of renal function in patients receiving ustekinumab, particularly those with preexisting kidney disease or risk factors for renal dysfunction.

Keywords: Crohn's disease; Renal insufficiency; Ustekinumab.

Publication types

  • Case Reports