Identification of the novel HLA-B*49:01:01:22 allele in an Indian renal transplant donor by next generation sequencing

HLA. 2024 Sep;104(3):e15665. doi: 10.1111/tan.15665.

Abstract

HLA-B*49:01:01:22 differs from HLA-B*49:01:01:01 by a single nucleotide C->G change in intron 5 at gDNA 2451.

Keywords: HLA; HLA‐B; Indian; NGS; novel allele.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Base Sequence
  • Exons
  • HLA-B39 Antigen / genetics
  • High-Throughput Nucleotide Sequencing*
  • Histocompatibility Testing* / methods
  • Humans
  • India
  • Introns*
  • Kidney Transplantation*
  • Polymorphism, Single Nucleotide
  • Sequence Analysis, DNA / methods
  • Tissue Donors*

Substances

  • HLA-B39 Antigen

Grants and funding