Perspectives on a peer-driven intervention to promote pre-exposure prophylaxis (PrEP) uptake among men who have sex with men in southern New England: a qualitative study

BMC Health Serv Res. 2024 Sep 4;24(1):1023. doi: 10.1186/s12913-024-11461-7.

Abstract

Background: Pre-exposure prophylaxis (PrEP) is a highly effective pharmaceutical intervention that prevents HIV infection, but PrEP uptake across the US has been slow among men who have sex with men (MSM), especially among Black/African American (B/AA) and Hispanic /Latino (H/L) MSM. This study investigates the acceptability and essential components of a peer-driven intervention (PDI) for promoting PrEP uptake among MSM, with a specific focus on B/AA and H/L communities.

Methods: We conducted 28 semi-structured, qualitative interviews with MSM in southern New England to explore the components of a PDI, including attitudes, content, and effective communication methods. A purposive sampling strategy was used to recruit diverse participants who reflect the communities with the highest burden of HIV infection.

Results: Of 28 study participants, the median age was 28 years (interquartile range [IQR]: 25, 35). The sample comprised B/AA (39%, n = 11) and H/L (50%, n = 14) individuals. Notably, nearly half of the participants (46%) were current PrEP users. We found that many participants were in favor of using a PDI approach for promoting PrEP. Additionally, several participants showed interest in becoming peer educators themselves. They emphasized the need for strong communication skills to effectively teach others about PrEP. Moreover, participants noted that peer education should cover key topics like how PrEP works, how effective it is, and any possible side effects.

Conclusions: Our study shows that effective PDIs, facilitated by well-trained peers knowledgeable about PrEP, could enhance PrEP uptake among MSM, addressing health disparities and potentially reducing HIV transmission in B/AA and H/L communities.

Keywords: Black/African American; HIV pre-exposure prophylaxis (PrEP); Hispanic/Latino; Men who have sex with men (MSM); Peer-driven intervention.

MeSH terms

  • Adult
  • Anti-HIV Agents / administration & dosage
  • Anti-HIV Agents / therapeutic use
  • Black or African American / psychology
  • Black or African American / statistics & numerical data
  • HIV Infections* / prevention & control
  • Hispanic or Latino / psychology
  • Hispanic or Latino / statistics & numerical data
  • Homosexuality, Male* / psychology
  • Homosexuality, Male* / statistics & numerical data
  • Humans
  • Interviews as Topic
  • Male
  • New England
  • Patient Acceptance of Health Care / psychology
  • Patient Acceptance of Health Care / statistics & numerical data
  • Peer Group*
  • Pre-Exposure Prophylaxis* / methods
  • Pre-Exposure Prophylaxis* / statistics & numerical data
  • Qualitative Research*

Substances

  • Anti-HIV Agents