Influence of CAD-CAM manufacturing methods on the accuracy and mechanical properties of implant-supported prostheses: A systematic review

Purpose: This systematic review aimed to provide comprehensive insights on the accuracy, fit, and mechanical characteristics of implant-supported computer-aided design and computer-aided manufacturing (CAD-CAM) prostheses, with a focus on milled and 3D-printed approaches.

Methods: The research question focused on implant-supported dental prostheses, comparing different manufacturing techniques (conventional, milled, and 3D-printed) to determine the different factors affecting the mechanical properties and fit of the CAD-CAM implant-supported prosthesis. The eligibility criteria encompassed studies involving implant-supported restorations, clear reporting of manufacturing techniques, and English-language publications from the last decade. The search was conducted across three main databases, MEDLINE, Scopus, and Web of Science in September 2023. Publication details, study characteristics, and methodological details of each included study were described.

Results: Of the initial 1964 articles, 581 met the inclusion criteria, and 104 studies were included in the final qualitative analysis. The majority of studies were conducted in the United States, Turkey, and Brazil. Fourteen studies evaluated accuracy parameters, while four studies focused on mechanical characteristics. The studies revealed variability in mechanical properties and marginal and internal fit, with fabrication methods impacting the structural integrity and stress distribution of the prostheses.

Conclusions: The findings suggest that digital manufacturing workflows, both milling and 3D printing, yield acceptable properties for implant-supported restorations with minimal variations in fit and accuracy. Notably, 3D printing and hybrid techniques demonstrate advantages in specific aspects like marginal fit and stress distribution. However, the milled prosthesis provided superior results in flexural strength and fracture resistance compared to conventional methods. Further research is needed to confirm these findings in clinical settings.