Advances in the Diagnosis and Treatment of Follicular Thyroid Carcinoma: A Comprehensive Review

Cureus. 2024 Aug 5;16(8):e66186. doi: 10.7759/cureus.66186. eCollection 2024 Aug.

Abstract

Follicular thyroid carcinoma (FTC) is the second most common type of thyroid cancer, presenting unique diagnostic and therapeutic challenges. This review provides a comprehensive analysis of the recent advancements in the diagnosis and treatment of FTC, emphasizing the significance of these developments in improving patient outcomes. We discuss the evolution of diagnostic techniques, including advancements in imaging modalities, fine needle aspiration biopsy, and molecular diagnostics, which have enhanced the accuracy of FTC detection and differentiation from benign conditions. The review also evaluates current treatment strategies, including surgical interventions, radioactive iodine therapy, and targeted therapies, examining their effectiveness and impact on patient prognosis. Additionally, we address ongoing challenges in FTC management, such as variability in treatment guidelines and disparities in care. Finally, the review explores emerging therapies and future research directions, highlighting innovations that may further optimize FTC management. By synthesizing current knowledge and identifying future research opportunities, this review aims to contribute to refining diagnostic and therapeutic approaches for FTC.

Keywords: diagnostic advances; follicular thyroid carcinoma; molecular diagnostics; targeted therapies; thyroid cancer management; treatment strategies.

Publication types

  • Review