Circulating Blood Plasma Profiling Reveals Proteomic Signature and a Causal Role for SVEP1 in Sudden Cardiac Death
Circ Genom Precis Med
.
2024 Oct;17(5):e004494.
doi: 10.1161/CIRCGEN.123.004494.
Epub 2024 Sep 5.
Authors
ThuyVy Duong
1
,
Thomas R Austin
2
3
,
Jennifer A Brody
2
,
Ali Shojaie
4
,
Alexis Battle
5
6
,
Joel S Bader
6
,
Yun Soo Hong
1
,
Christie M Ballantyne
7
,
Josef Coresh
8
,
Robert E Gerszten
9
,
Russell P Tracy
10
,
Bruce M Psaty
2
3
11
,
Nona Sotoodehnia
2
,
Dan E Arking
1
Affiliations
1
McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (T.D., Y.S.H., D.E.A.).
2
Cardiovascular Health Research Unit, Department of Medicine (T.R.A., J.A.B., B.M.P., N.S.), University of Washington, Seattle.
3
Department of Epidemiology (T.R.A., B.M.P.), University of Washington, Seattle.
4
Department of Biostatistics (A.S.), University of Washington, Seattle.
5
Department of Computer Science (A.B.), Johns Hopkins University, Baltimore, MD.
6
Department of Biomedical Engineering (A.B., J.S.B.), Johns Hopkins University, Baltimore, MD.
7
Department of Medicine, Baylor College of Medicine and the Texas Heart Institute, Houston (C.M.B.).
8
Department of Population Health, New York University Grossman School of Medicine (J.C.).
9
Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (R.E.G.).
10
Department of Pathology and Laboratory Medicine and Biochemistry, Larner College of Medicine, University of Vermont, Burlington (R.P.T.).
11
Department of Health Systems and Population Health (B.M.P.), University of Washington, Seattle.
PMID:
39234668
PMCID:
PMC11479847
(available on
2025-10-01
)
DOI:
10.1161/CIRCGEN.123.004494
No abstract available
Keywords:
atherosclerosis; biomarkers; death, sudden, cardiac; heart; risk factors.
Publication types
Review
MeSH terms
Death, Sudden, Cardiac*
Humans
Proteomics*
Grants and funding
U01 HL130114/HL/NHLBI NIH HHS/United States
HHSN268200800007C/HL/NHLBI NIH HHS/United States
R01 HL086694/HL/NHLBI NIH HHS/United States
N01HC85086/HL/NHLBI NIH HHS/United States
R01 HL105756/HL/NHLBI NIH HHS/United States
75N92022D00004/HL/NHLBI NIH HHS/United States
75N92022D00003/HL/NHLBI NIH HHS/United States
75N92022D00001/HL/NHLBI NIH HHS/United States
R01 HL141989/HL/NHLBI NIH HHS/United States
N01HC85081/HL/NHLBI NIH HHS/United States
UL1 RR025005/RR/NCRR NIH HHS/United States
75N92022D00002/HL/NHLBI NIH HHS/United States
U01 HL080295/HL/NHLBI NIH HHS/United States
U01 HG004402/HG/NHGRI NIH HHS/United States
N01HC55222/HL/NHLBI NIH HHS/United States
HHSN268201200036C/HL/NHLBI NIH HHS/United States
R01 HL144483/HL/NHLBI NIH HHS/United States
HHSN268201800001C/HL/NHLBI NIH HHS/United States
75N92021D00006/HL/NHLBI NIH HHS/United States
75N92022D00005/HL/NHLBI NIH HHS/United States
N01HC85082/HL/NHLBI NIH HHS/United States
N01HC85083/HL/NHLBI NIH HHS/United States
R01 HL144569/HL/NHLBI NIH HHS/United States
N01HC85079/HL/NHLBI NIH HHS/United States
R01 AG023629/AG/NIA NIH HHS/United States
R01 HL087641/HL/NHLBI NIH HHS/United States
R01 HL134320/HL/NHLBI NIH HHS/United States
N01HC85080/HL/NHLBI NIH HHS/United States