A Review of the Indications, Outcomes, and Postoperative Management After Total and Completion Pancreatectomy for Pancreatic Cancer: More Is Not Necessarily Better

Kailey M Oppat; Frances J Bennett; Shishir K Maithel

doi:10.1016/j.suc.2024.04.012

A Review of the Indications, Outcomes, and Postoperative Management After Total and Completion Pancreatectomy for Pancreatic Cancer: More Is Not Necessarily Better

Surg Clin North Am. 2024 Oct;104(5):1049-1064. doi: 10.1016/j.suc.2024.04.012. Epub 2024 May 23.

Authors

Kailey M Oppat¹, Frances J Bennett¹, Shishir K Maithel²

Affiliations

¹ Emory University, 1365B Clifton Road, NE Building B, Suite 4100, Office 4202, Atlanta, GA 30302, USA.
² Emory University, 1365B Clifton Road, NE Building B, Suite 4100, Office 4202, Atlanta, GA 30302, USA. Electronic address: [email protected].

PMID: 39237163
DOI: 10.1016/j.suc.2024.04.012

Abstract

With improvements in surgical technique and advances in pancreatic endocrine and exocrine replacement therapy, the indications for, and threshold to perform, total or completion pancreatectomy in the modern surgical era are ever evolving. The following review will evaluate such indications for pancreatic cancer including pancreatic ductal adenocarcinoma and intraductal papillary mucinous neoplasms. The authors also review the literature on oncologic outcomes of total and completion pancreatectomy for pancreatic cancer. Finally, they discuss the quality of life and postoperative management of the a-pancreatic state.

Keywords: Completion pancreatectomy; Indications; Outcomes; Postoperative management; Total pancreatectomy.

Publication types

Review

MeSH terms

Carcinoma, Pancreatic Ductal / surgery
Humans
Pancreatectomy* / methods
Pancreatic Neoplasms* / surgery
Postoperative Care / methods
Postoperative Complications / epidemiology
Postoperative Complications / etiology
Quality of Life
Treatment Outcome