Pancreas Cyst Diagnosis and Advances in Cyst Fluid Analysis

Tommaso Pollini; Letizia Todeschini; Ajay V Maker

doi:10.1016/j.suc.2024.03.003

Pancreas Cyst Diagnosis and Advances in Cyst Fluid Analysis

Surg Clin North Am. 2024 Oct;104(5):965-974. doi: 10.1016/j.suc.2024.03.003. Epub 2024 Apr 23.

Authors

Tommaso Pollini¹, Letizia Todeschini¹, Ajay V Maker²

Affiliations

¹ Division of Surgical Oncology, Department of Surgery, University of California San Francisco.
² Division of Surgical Oncology, Department of Surgery, University of California San Francisco. Electronic address: [email protected].

PMID: 39237171
DOI: 10.1016/j.suc.2024.03.003

Abstract

Pancreatic Cystic Neoplasms (PCN) represent a diverse group of tumors, some of which may progress to pancreatic cancer. Considering their high prevalence in the general population, the development of reliable biomarkers is crucial. The ideal biomarker will accurately diagnose the subtype of PCN and assess the risk of high-grade dysplasia or invasive cancer. Cyst fluid analysis has emerged as a promising approach to accomplish this goal, yet no single marker has yet gained unanimous support for routine inclusion in PCN evaluation.

Keywords: Cyst fluid; IPMN; Intraductal papillary mucinous neoplasms; Pancreatic cancer; Pancreatic cystic neoplams.

Publication types

Review

MeSH terms

Biomarkers, Tumor / analysis
Biomarkers, Tumor / metabolism
Cyst Fluid* / chemistry
Humans
Pancreatic Cyst* / diagnosis
Pancreatic Neoplasms* / diagnosis

Substances

Biomarkers, Tumor