An Aggressively Recurrent Squamous Cell Carcinoma of the Foot

J Am Podiatr Med Assoc. 2024 Jul-Aug;114(4):21-044A. doi: 10.7547/21-044A.

Abstract

Squamous cell carcinoma is a malignant tumor that is most commonly found on the head and neck. The current global incidence of squamous cell carcinoma at any site is estimated to be more than 1 million cases per year, with a reported 3-year mortality rate of 30%. Recurrence of squamous cell carcinoma at any site is estimated to be 15% to 50% and has been associated with greater rates of infiltration, perineural invasion, and mortality. Recent studies have shown lower-extremity squamous cell carcinoma to be distinct from squamous cell carcinoma at any site with histologic and clinical differences. Lower-extremity squamous cell carcinoma is suggestively less aggressive and carries less risk of metastasis. However, lower-extremity squamous cell carcinoma prevalence, mortality, and recurrence rates have not been extensively studied. The present report depicts a case of recurrent squamous cell carcinoma originating in 2006 in the dorsal forefoot and provides the clinical management of subsequent recurrence episodes, with excisions from 2015 and 2020.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Squamous Cell* / pathology
  • Carcinoma, Squamous Cell* / surgery
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local*
  • Skin Neoplasms / pathology
  • Skin Neoplasms / surgery