Let's not abandon programmed frozen embryo transfers yet: a countercurrent perspective

Reprod Biomed Online. 2024 Nov;49(5):104365. doi: 10.1016/j.rbmo.2024.104365. Epub 2024 Jul 6.

Abstract

The countercurrent opinion given in this paper is that the optimal management of frozen embryo transfers (FET) is not a one-size-fits-all matter, but rather one that should be decided after considering all the various parameters and options. This choice should notably encompass patients' individual characteristics - including variable risks of obstetric complications - and weigh out the respective advantages of each FET option in each case. While there may be real advantages for natural-cycle FET in many cases, these need to be balanced against both practical and clinical issues. Contrary to several prevailing, sometimes loudly expressed suggestions, there is not a one single effective approach when it comes to choosing a mode of scheduling FET.

Keywords: Adenomyosis; Endometriosis; Frozen embryo transfer; Oestradiol and progesterone programming; Pre-eclampsia.

MeSH terms

  • Cryopreservation*
  • Embryo Transfer* / methods
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Rate