Tailoring molecularly imprinted polymer on titanium-multiwalled carbon nanotube functionalized gold electrode for enhanced chlorophyll determination in microalgae health assessment

Mikrochim Acta. 2024 Sep 10;191(10):586. doi: 10.1007/s00604-024-06662-0.

Abstract

A unique method for determining chlorophyll content in microalgae is devised employing a gold interdigitated electrode (G-IDE) with a 10-µm gap, augmented by a nano-molecularly imprinted polymer (nano-MIP) and a titanium dioxide/multiwalled carbon nanotube (TiO2/MWCNT) nanocomposite. The nano-MIP, produced using chlorophyll template voids, successfully trapped chlorophyll, while the TiO2/MWCNT nanocomposite, synthesized by the sol-gel technique, exhibited a consistent distribution and anatase crystalline structure. The rebinding of procured chlorophyll powder, which was used as a template for nano-MIP synthesis, was identified with a high determination coefficient (R2 = 0.9857). By combining the TiO2/MWCNT nanocomposite with nano-MIP, the G-IDE sensing method achieved a slightly better R2 value of 0.9892 for detecting chlorophyll in microalgae. The presented G-IDE sensor showed a significant threefold enhancement in chlorophyll detection compared with commercially available chlorophyll powder. It had a detection limit of 0.917 mL (v/v) and a linear range that spanned from 10-6 to 1 mL. The effectiveness of the sensor in detecting chlorophyll in microalgae was confirmed through validation of its repeatability and reusability.

Keywords: Chlorella vulgaris; Health management; Nanocomposite; Nanosensor; Polymer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chlorophyll* / analysis
  • Chlorophyll* / chemistry
  • Electrochemical Techniques* / instrumentation
  • Electrochemical Techniques* / methods
  • Electrodes*
  • Gold* / chemistry
  • Limit of Detection
  • Microalgae* / chemistry
  • Molecular Imprinting
  • Molecularly Imprinted Polymers* / chemistry
  • Nanotubes, Carbon* / chemistry
  • Titanium* / chemistry

Substances

  • Titanium
  • Nanotubes, Carbon
  • Gold
  • Chlorophyll
  • titanium dioxide
  • Molecularly Imprinted Polymers