Staphylococcus aureus exacerbates dermal IL-33/ILC2 axis activation through evoking RIPK3/MLKL-mediated necroptosis of dry skin

JCI Insight. 2024 Sep 10;9(17):e185878. doi: 10.1172/jci.insight.185878.

Authors

Chia-Hui Luo, Alan Chuan-Ying Lai, Chun-Chou Tsai, Wei-Yu Chen, Yu-Shan Chang, Ethan Ja-Chen Chung, Ya-Jen Chang

No abstract available

MeSH terms

Animals
Female
Humans
Interleukin-33* / genetics
Interleukin-33* / metabolism
Male
Mice
Necroptosis*
Protein Kinases* / metabolism
Receptor-Interacting Protein Serine-Threonine Kinases* / genetics
Receptor-Interacting Protein Serine-Threonine Kinases* / metabolism
Skin / metabolism
Skin / microbiology
Skin / pathology
Staphylococcal Infections / immunology
Staphylococcal Infections / metabolism
Staphylococcal Infections / microbiology
Staphylococcus aureus*

Substances

Interleukin-33
Receptor-Interacting Protein Serine-Threonine Kinases
Protein Kinases
Ripk3 protein, mouse
MLKL protein, mouse
Il33 protein, mouse