Successful dental implant therapy relies on a bone-implant interface that is mechanically strong and capable of dynamic remodeling in response to functional loads. There are a number of medical conditions or therapies that can affect either bone metabolism or the resistance of bone to infection. However, their effects are often mitigated by local factors or individual responses so the impact of these conditions is not clear-cut. This article will review a number of these conditions and therapies and describe existing studies that have studied these conditions to guide practitioners in their implant practice.
Keywords: Diabetes; Implant osseointegration; Implant success rate; Implant survival; Inflammatory bowel disease; Medical status; Proton pump inhibitors; Systemic diseases.
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