Endoscopic and Pharmacologic Treatment of Obesity in Patients With Hereditary Polyposis Syndromes

ACG Case Rep J. 2024 Sep 12;11(9):e01514. doi: 10.14309/crj.0000000000001514. eCollection 2024 Sep.

Abstract

Patients with hereditary polyposis syndromes (HPS) are among the highest risk of multiple types of cancer. This risk is further magnified by comorbid obesity; however, HPS present unique risks for bariatric surgery. The advent of endoscopic bariatric and metabolic therapies along with advancements in the realm of antiobesity medications provides potential weight loss alternatives in this vulnerable population. We present 2 cases of patients with obesity and HPS successfully treated with intragastric balloons in combination with antiobesity medications.

Keywords: bariatric endoscopy; hereditary polyposis; intragastric balloon; obesity.

Publication types

  • Case Reports