Acute toxicity of chlorpyrifos to some non-target freshwater organisms: which one is more toxic-technical grade or commercial formulation?

Ecotoxicology. 2024 Dec;33(10):1171-1179. doi: 10.1007/s10646-024-02806-3. Epub 2024 Sep 13.

Abstract

Chlorpyrifos is among the most widely sold organophosphates in the agriculture sector worldwide. Static bioassays were performed in the laboratory to compare the acute toxicity between the technical grade (94% a.i.) and commercial formulation (20% EC) of chlorpyrifos to four freshwater organisms: the crustacean zooplankton Cyclops viridis, the oligochaete worm Branchiura sowerbyi, the gastropod Pila globosa, and tadpole larvae of Duttaphrynus melanostictus. The recovery of actual chlorpyrifos concentrations in water after 2 h of exposure to the nominal concentrations ranged from 82.98% to 88.56%. The commercial formulation (F) of chlorpyrifos was found to be 1.94 to 2.76 times more toxic than the technical grade (T). Based on 96 h LC50 values of T and F chlorpyrifos, C. viridis was found to be most sensitive (0.56 and 0.25 μg/L) and P. globosa as most tolerant (1482 and 536 μg/L) to chlorpyrifos. Changes in LC50 values of both T and F chlorpyrifos were noted in respect of exposure hours for the three aquatic invertebrates and the tadpole larvae of the toad. In conclusion, the acute toxicity of chlorpyrifos to some non-target freshwater organisms differs between technical grade and commercial formulations.

Keywords: Aquatic Organisms; Formulation; LC50; Organophosphates; Toxicity.

MeSH terms

  • Animals
  • Aquatic Organisms / drug effects
  • Chlorpyrifos* / toxicity
  • Fresh Water*
  • Gastropoda / drug effects
  • Insecticides* / toxicity
  • Larva / drug effects
  • Larva / growth & development
  • Lethal Dose 50
  • Oligochaeta / drug effects
  • Toxicity Tests, Acute
  • Water Pollutants, Chemical* / toxicity
  • Zooplankton / drug effects

Substances

  • Chlorpyrifos
  • Water Pollutants, Chemical
  • Insecticides