Magnetic Induction Heating in a Conducting Polymer for Biomedical Applications

ACS Nano. 2024 Oct 1;18(39):26600-26613. doi: 10.1021/acsnano.4c04717. Epub 2024 Sep 16.

Abstract

In this study, we investigate the magnetic induction heating induced in a conducting polymer (CP) under alternative magnetic fields (AMFs). Experimental results and numerical simulations have proved that the magneto-thermal conversion of the CP is caused by the induced eddy current, which is related to the shape and intensity of the applied external AMF, and the intrinsic electrical conductivity, macrostructure and microstructure of the CP. By employing various fabrication methods, specific temperature distribution and control of thermal field within conducting polymer films and aerogels could be achieved. To exploit the potential of magnetic induction heating in CP for biomedical applications, we designed a conducting polymer aerogel-based self-adaptive heat patch and demonstrated its AMF-enabled localized heating of skin. In addition to the thermal ablation of tumor cells via magneto-thermal conversion of the CP, the promotion of neuronal differentiation at mild temperature by noninvasive magneto-electrical stimulation has also been demonstrated to be an effective strategy for tissue engineering.

Keywords: conducting polymer; eddy current; magnetic induction heating; neuronal differentiation; thermal ablation.

MeSH terms

  • Animals
  • Electric Conductivity*
  • Heating
  • Hot Temperature
  • Humans
  • Magnetic Fields*
  • Mice
  • Polymers* / chemistry
  • Tissue Engineering

Substances

  • Polymers