Resolution of Severe Ulcerative Colitis Secondary to Nickel Allergy Following Explantation of Amplatzer Septal Occluder Device: A Delayed Presentation

World J Pediatr Congenit Heart Surg. 2025 Jan;16(1):119-121. doi: 10.1177/21501351241269861. Epub 2024 Sep 17.

Abstract

Nickel is a component of nitinol, an alloy used in several medical devices. Allergy to nickel may place patients at a high risk for severe hypersensitivity reactions. We report a rare case of a patient who developed severe ulcerative colitis ten years following closure of an atrial septal defect with the Amplatzer Septal Occluder device.

Keywords: Amplatzer device; congenital; nickel allergy; pediatric; pediatric surgery; ulcerative colitis; valve disease; valve replacement.

Publication types

  • Case Reports

MeSH terms

  • Colitis, Ulcerative* / surgery
  • Device Removal*
  • Female
  • Heart Septal Defects, Atrial* / surgery
  • Humans
  • Hypersensitivity / etiology
  • Male
  • Nickel* / adverse effects
  • Septal Occluder Device* / adverse effects

Substances

  • Nickel