The f-sum rules set general constraints on the response of a quantum many-body system to an external probe and hold significant relevance in the realm of various spectroscopy measurements. In practical conditions, a system unavoidably couples with the environment and acquires effective dissipation. In this Letter, we derive and prove a set of f-sum rules for dissipative systems. Within the framework of linear response theory, we obtain the system response in both linear order of probe field and dissipation parameter. We formulate and prove one first-order and two second-order dissipative f-sum rules. These rules are validated numerically for some example models, and the realization schemes are proposed. In addition, the potential applications are discussed for two interacting many-body systems.