Sinonasal Pathologies Masquerading as Ophthalmic Disease

Ear Nose Throat J. 2024 Sep;103(2_suppl):16S-21S. doi: 10.1177/01455613241281561. Epub 2024 Sep 20.

Abstract

This report presents 2 illustrative cases of sinonasal pathologies masquerading as ocular diseases: one of a 43-year-old male with a frontoethmoidal mucocele resulting from multiple prior surgeries for juvenile nasopharyngeal angiofibroma, and the other of a 72-year-old male with sinonasal diffuse large B-cell lymphoma, both presenting primarily with ocular symptoms including diplopia and visual disturbance. Through these cases, we highlight the importance of considering sinonasal pathologies in the differential diagnosis of patients presenting with ocular symptoms and discuss the diagnostic and therapeutic approaches that enabled effective disease management. Multidisciplinary collaboration involving otolaryngologists, ophthalmologists, radiologists, and oncologists was critical in achieving accurate diagnoses and successful management of these sinonasal diseases with ocular involvement.

Keywords: orbital mass; paranasal sinus mucocele; sinonasal lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Angiofibroma* / diagnosis
  • Angiofibroma* / pathology
  • Angiofibroma* / surgery
  • Diagnosis, Differential
  • Diplopia / etiology
  • Humans
  • Lymphoma, Large B-Cell, Diffuse / diagnosis
  • Lymphoma, Large B-Cell, Diffuse / pathology
  • Male
  • Mucocele* / diagnosis
  • Mucocele* / surgery
  • Nasopharyngeal Neoplasms / diagnosis
  • Nasopharyngeal Neoplasms / surgery
  • Paranasal Sinus Diseases / diagnosis
  • Paranasal Sinus Diseases / diagnostic imaging
  • Paranasal Sinus Diseases / surgery
  • Paranasal Sinus Neoplasms / diagnosis
  • Paranasal Sinus Neoplasms / pathology
  • Paranasal Sinus Neoplasms / surgery
  • Vision Disorders / diagnosis
  • Vision Disorders / etiology