Objective: To verify the consistency between changes in Mandarin Tinnitus Questionnaire (MTQ) scores and tinnitus treatment outcomes. Methods: Tinnitus patients attending the Department of Otorhinolaryngology-Head & Neck Surgery, West China Hospital of Sichuan University from September 2020 to September 2021were prospectively enrolled. The tinnitus severity was evaluated by the doctor's assessment, the patient's self-assessment, the MTQ, and the Visual Analogue Scale (VAS). Follow-up assessments were conducted 3 to 6 months later to evaluate the severity of tinnitus post-treatment, and information on the interventions received (pharmacologic/non-pharmacologic) and patients' self-reported clinical impressions of their treatment outcomes (tinnitus cured/improved/no change/exacerbated) was collected. Results: A total of 54 tinnitus patients aged (43.5±12.7) years were included, consisting of 16 males and 38 females. There were 38 cases in the medication group and 16 cases in the non-medication group. No statistically significant differences in baseline clinical data were observed (all P>0.05). The proportion of primary tinnitus in the medication group was higher than that in the non-medication group [97.4% (37/38) vs 75.0% (12/16), P=0.023]. The correlation coefficients of MTQ scores at the initial and follow-up visits with doctor's assessment, patient's self-assessment, and VAS scores were 0.679, 0.483, 0.606, 0.774, 0.779, and 0.756, respectively (all P<0.001). The ΔMTQ correlation coefficient with ΔVAS was 0.694 (P<0.001), with a mean difference of 3.704×10-7 and 95% limits of agreement ranging from -1.534 to 1.534 in Bland-Altman analysis. There were no statistically significant differences of ΔVAS and ΔMTQ between two groups (both P>0.05). Conclusions: MTQ correlates well with the doctor's assessment, the patient's self-assessment, and VAS. Changes in MTQ scores associate well with changes in VAS scores. Additionally, changes in MTQ scores are consistent with the effect of tinnitus treatment.
目的： 验证普通话版耳鸣问卷（MTQ）评分变化与耳鸣治疗效果的一致性。 方法： 前瞻性纳入2020年9月至2021年9月在四川大学华西医院耳鼻咽喉头颈外科就诊的耳鸣患者，通过医师评估、患者自评、MTQ和视觉模拟量表（VAS）对患者耳鸣严重程度进行评估。治疗3~6个月后进行随访，评估患者治疗后耳鸣严重程度，收集患者接受的干预治疗手段［药物治疗（药物组）/非药物治疗（非药物组）］、治疗后的自我临床印象（耳鸣治愈/改善/无变化/加重），评估MTQ评分变化与耳鸣治疗效果的一致性。 结果： 共纳入54例耳鸣患者，其中男16例，女38例，年龄（43.5±12.7）岁。药物组38例，非药物组16例；药物治疗组原发性耳鸣比例高于非药物治疗组［97.4%（37/38）比75.0%（12/16），P=0.023］，其余基线临床资料差异均无统计学意义（均P>0.05）。初诊、复诊时MTQ评分与医师评估（r=0.679、0.774）、患者自评（r=0.483、0.779）及VAS（r=0.606、0.756）得分均呈正相关（均P<0.001）。治疗后MTQ评分变化值（ΔMTQ）与VAS得分变化值（ΔVAS）呈正相关（r=0.694，P<0.001）；Bland-Altman分析结果显示，ΔMTQ与ΔVAS的平均差值为3.704×10-7，95%的一致性界限为-1.534~1.534；药物组与非药物组ΔVAS、ΔMTQ差异均无统计学意义（均P>0.05）。 结论： 耳鸣患者MTQ评分与医师评估、患者自评及VAS得分相关性良好，MTQ评分变化与耳鸣治疗效果一致。.