Invasive lobular carcinoma of the male breast: A case report

Radiol Case Rep. 2024 Sep 12;19(12):5758-5761. doi: 10.1016/j.radcr.2024.08.063. eCollection 2024 Dec.

Abstract

Invasive lobular carcinoma (ILC) is a rare type of male breast cancer, representing about 1% of cases. It often presents with a palpable mass and sometimes nipple changes, but is usually diagnosed late. ILC is more likely to be estrogen and progesterone receptor-positive and usually HER-2 negative. Its diffuse growth pattern makes it difficult to detect with imaging. Treatment typically follows protocols for female breast cancer, including surgery, chemotherapy, and hormone therapy, with tamoxifen being commonly used. Further research is needed to better understand its pathogenesis and to develop more effective, tailored treatments.

Keywords: Breast ultrasound; E-cadherin; Histology; Lobular breast carcinoma; Male breast cancer.

Publication types

  • Case Reports