A novel HLA-DQB106 variant allele, HLA-DQB106:02:01:40, identified by next-generation sequencing

HLA. 2024 Sep;104(3):e15706. doi: 10.1111/tan.15706.

Authors

Diamanto Kouniaki¹, Katerina Tarassi¹, Alexandra Tsirogianni¹

Affiliation

¹ Immunology and Histocompatibility Department, Evangelismos General Hospital, Athens, Greece.

PMID: 39311807
DOI: 10.1111/tan.15706

Abstract

The HLA-DQB1*06:02:01:40 allele differs from HLA-DQB1*06:02:01:01 by a single nucleotide substitution in intron 2.

Keywords: HLA‐DQB1*06:02:01:40 novel allele; Illumina; next‐generation sequencing.

© 2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles*
Base Sequence
Exons
HLA-DQ beta-Chains* / genetics
High-Throughput Nucleotide Sequencing*
Histocompatibility Testing* / methods
Humans
Introns*
Polymorphism, Single Nucleotide
Sequence Analysis, DNA / methods

Substances

HLA-DQ beta-Chains
HLA-DQB1 antigen