Localized electrocortical activity as a function of single-leg squat phases and its relationship to knee frontal plane stability

Exp Brain Res. 2024 Nov;242(11):2583-2597. doi: 10.1007/s00221-024-06927-3. Epub 2024 Sep 23.

Abstract

This study investigated differences in electroencephalography (EEG) activity within motor-related brain areas during three phases of a single-leg squat (SLS)-i.e., descending, holding, and ascending phases. Specifically, utilizing advanced magnetic resonance imaging guided EEG source localization techniques and markerless motion capture technology, we explored the interplay between concurrently recorded lower-extremity biomechanics and brain activity. Among the phases of a nondominant leg SLS, differences in contralateral brain activity (right hemisphere) were found in the activity of the precentral gyrus, the postcentral gyrus, and the sensory motor area. Alternatively, during the dominant SLS leg, differences among the three SLS phases in contralateral brain activity were fewer. Hemispheric dependent brain activity also significantly correlated with participants' knee valgus angle range of motion (right hemisphere) and peak knee valgus angles (left hemisphere). In addition to the novel brain and biomechanical findings, this study sheds light on the technical feasibility of recording EEG during complex multi-joint movements and its potential applications in understanding sensorimotor behavior.

Keywords: EEG; MRI; Motion capture; Squat.

MeSH terms

  • Adult
  • Biomechanical Phenomena / physiology
  • Brain Mapping / methods
  • Electroencephalography* / methods
  • Female
  • Functional Laterality / physiology
  • Humans
  • Knee / physiology
  • Knee Joint / physiology
  • Leg / physiology
  • Magnetic Resonance Imaging
  • Male
  • Movement / physiology
  • Range of Motion, Articular / physiology
  • Young Adult