Clinicopathologic description of a cutaneous melanocytic tumor in a 1-year-old cat

Vet Clin Pathol. 2024 Sep;53(3):369-373. doi: 10.1111/vcp.13361. Epub 2024 Jun 21.

Abstract

A feline cutaneous melanocytic tumor in a 1-year-old cat is reported. The cytologic, histologic, and immunohistochemical characteristics of the pediatric feline cutaneous melanocytoma are included. A solitary, black-colored nodule on the head was histologically diagnosed as the epithelioid type of melanocytoma. Immunohistochemically, the neoplastic melanocytes demonstrated immunoreactivity to the S100 and MelanA antibodies but not to the PNL2 antibody. Despite high mitotic counts (17/10HPFs) and a Ki67 index (33%) suggesting malignant melanoma, the patient exhibited a favorable 5-month outcome. The mitotic activity of the neoplastic cells may not provide a reliable prediction for feline melanocytic tumors.

Keywords: case report; feline; immunohistochemistry; melanocytoma; pediatric tumor.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Cat Diseases* / diagnosis
  • Cat Diseases* / pathology
  • Cats
  • Female
  • Immunohistochemistry / veterinary
  • Male
  • Melanocytes / pathology
  • Melanoma* / diagnosis
  • Melanoma* / pathology
  • Melanoma* / veterinary
  • Skin Neoplasms* / diagnosis
  • Skin Neoplasms* / pathology
  • Skin Neoplasms* / veterinary