Are integrated care models associated with improved drug safety in Swiss primary care? an observational analysis using healthcare claims data

PLoS One. 2024 Sep 26;19(9):e0311099. doi: 10.1371/journal.pone.0311099. eCollection 2024.

Abstract

Background: Integrated care models (ICMs) might be an effective strategy to improve patients' quality of care. The aim of this study was to compare different ICMs such as family-doctor models, and a standard care model (SCM) regarding patients' drug safety in Swiss primary care.

Methods: We performed an observational study using health insurance claims data from patients who were continuously enrolled in an ICM or in a SCM between 2020 and 2021. ICMs included family-doctor model (FDM), family-doctor model light (FDM-light) and the telemedicine model (TM). Drug safety was assessed by the prescription of potentially inappropriate proton pump-inhibitors (PIPPI), opioids (PIO), medications (PIM), and polypharmacy. Propensity-score-weighted multiple logistic regression models were used to examine the association between different types of ICMs and drug safety.

Results: Patients in FDM had significantly lower odds of receiving PIPPI (OR, 0.86; CI 95%, 0.83-0.89), PIO (OR, 0.81; CI 95%, 0.76-0.85), PIM (OR, 0.94; CI 95%, 0.91-0.97), and polypharmacy (OR, 0.94; CI 95%, 0.91-0.97) compared to patients in SCM. Potentially inappropriate prescribing was also lower in patients in TM and partly in FDM-light than in SCM. Persons enrolled in FDM were less likely to receive PIM (OR, 0.93; CI 95%, 0.89-0.97) and polypharmacy (OR, 0.94; CI 95%, 0.90-0.99) than those in FDM-light, whereas the odds of receiving PIPPI and polypharmacy were higher in FDM than in TM.

Conclusion: ICMs were significantly associated with higher drug safety compared to SCM for most outcomes. Findings suggest that patients may benefit most from ICMs with a high degree of coordination or gatekeeping. ICM may represent an effective approach to improve patients' drug safety and, thus, to reduce the risk of adverse events.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Analgesics, Opioid / adverse effects
  • Analgesics, Opioid / therapeutic use
  • Delivery of Health Care, Integrated
  • Drug-Related Side Effects and Adverse Reactions
  • Female
  • Humans
  • Male
  • Middle Aged
  • Polypharmacy
  • Primary Health Care*
  • Proton Pump Inhibitors / adverse effects
  • Proton Pump Inhibitors / therapeutic use
  • Switzerland
  • Young Adult

Substances

  • Analgesics, Opioid
  • Proton Pump Inhibitors

Grants and funding

The author(s) received no specific funding for this work.