Rejoinder to the discussion on "LEAP: the latent exchangeability prior for borrowing information from historical data"

Ethan M Alt; Xiuya Chang; Xun Jiang; Qing Liu; May Mo; Hong Amy Xia; Joseph G Ibrahim

doi:10.1093/biomtc/ujae087

Rejoinder to the discussion on "LEAP: the latent exchangeability prior for borrowing information from historical data"

Biometrics. 2024 Jul 1;80(3):ujae087. doi: 10.1093/biomtc/ujae087.

Authors

Ethan M Alt¹, Xiuya Chang¹, Xun Jiang², Qing Liu², May Mo², Hong Amy Xia², Joseph G Ibrahim¹

Affiliations

¹ Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, United States.
² Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, United States.

PMID: 39329229
DOI: 10.1093/biomtc/ujae087

Abstract

The discussions of our paper provide insights into the practical considerations of the latent exchangeability prior while also highlighting further extensions. In this rejoinder, we briefly summarize the discussions and provide comments.

Keywords: Bayesian dynamic borrowing; clinical trials; external data; historical data; latent exchangeability prior.

MeSH terms

Biometry / history
Biometry / methods
Data Interpretation, Statistical
Humans
Models, Statistical*