Post traumatic stress and sleep disorders in long COVID: Patient management and treatment

Life Sci. 2024 Nov 15:357:123081. doi: 10.1016/j.lfs.2024.123081. Epub 2024 Sep 26.

Abstract

Post traumatic stress disorder (PTSD) and sleep disorders are prevalent among patients with long COVID. The intersection of PTSD and/or sleep disorders with long COVID is complex. Thus, use of a biopsychosocial lens for assessment and treatment along with a trauma-informed approach to clinical care is recommended. This review provides an overview of the literature on PTSD and sleep disorders among patients with long COVID, including prevalence rates, risk factors, and potential pathophysiology. Pharmacological and non-pharmacological treatment options are reviewed. Also, we provide actionable steps clinicians can integrate into their practice to help effectively assess and treat PTSD and sleep disorders, including validated symptom assessments, recommended referrals, and specific components of non-pharmacological interventions.

Keywords: Long COVID; Post-traumatic stress disorder; Self-management; Sleep disorder; Sleep hygiene.

Publication types

  • Review

MeSH terms

  • COVID-19* / complications
  • COVID-19* / therapy
  • Humans
  • Risk Factors
  • SARS-CoV-2
  • Sleep Wake Disorders* / therapy
  • Stress Disorders, Post-Traumatic* / physiopathology
  • Stress Disorders, Post-Traumatic* / therapy