Pain-free today, weak tomorrow: a case of electrolyte disorder due to diclofenac misuse

BMC Nephrol. 2024 Sep 27;25(1):317. doi: 10.1186/s12882-024-03759-9.

Abstract

Background: The nephrotoxic effects of non-steroidal anti-inflammatory drugs (NSAIDs) are widely acknowledged. In particular, diclofenac is the most commonly prescribed NSAIDs, but no previous findings of electrolyte disturbances were reported following its administration.

Case report: We presented the case of a man who experienced significant weakness associated with severe deficiencies in potassium, calcium, and magnesium after misusing diclofenac because of severe back pain.

Conclusions: This case emphasizes the need of awareness about the electrolyte imbalances and electrolyte disturbances associated with the misuse of diclofenac, which is a widely available drug. This is a case report which does not need a Clinical Trial Number.

Keywords: Diclofenac; Electrolyte disorder; NSAIDs.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal* / adverse effects
  • Back Pain / drug therapy
  • Diclofenac* / adverse effects
  • Humans
  • Male
  • Middle Aged
  • Water-Electrolyte Imbalance* / chemically induced

Substances

  • Diclofenac
  • Anti-Inflammatory Agents, Non-Steroidal