The effect of diets with different inflammatory scores on inflammation and sleep in obese subjects: a randomized controlled trial

Rev Assoc Med Bras (1992). 2024 Sep 30;70(10):e20240588. doi: 10.1590/1806-9282.20240588. eCollection 2024.

Abstract

Objective: The aim of this study was to investigate the effect of different dietary inflammatory index diets on inflammatory markers, anthropometric measurements, and sleep quality in obese subjects.

Methods: This study was conducted in a public hospital in Turkey between November 2021 and May 2022. Participants with pro-inflammatory dietary habits were included in the study. Randomly divided into two groups of 33 participants, they were subjected to an anti-inflammatory diet or a control diet for 8 weeks. The study evaluated the anthropometric parameters, inflammatory biomarkers, and sleep quality indices of the diet groups.

Results: Significant reductions in body mass index were observed in both groups, more marked in the anti-inflammatory diet cohort. C-reactive protein levels, indicative of inflammation, also decreased substantially in both groups, with a more marked reduction in the anti-inflammatory diet cohort. Despite the improvement in sleep quality in both groups, the variation was not statistically significant.

Conclusion: This study demonstrates the importance of anti-inflammatory diets in nutritional strategies for obesity by reducing body mass index and inflammation.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Biomarkers / analysis
  • Biomarkers / blood
  • Body Mass Index*
  • C-Reactive Protein* / analysis
  • Diet
  • Female
  • Humans
  • Inflammation* / diet therapy
  • Male
  • Middle Aged
  • Obesity* / complications
  • Obesity* / diet therapy
  • Sleep / physiology
  • Sleep Quality*
  • Treatment Outcome

Substances

  • C-Reactive Protein
  • Biomarkers