Background: Aberrant tissue repair can result in the formation of chronic wounds and pathological scarring, which can severely impact a patient's quality of life. Due to their complexity, treatment of these conditions remains challenging.
Purpose: This review article provides a brief overview of the various treatments with regards to application, possible mechanism(s) of action, new developments, and areas requiring further research.
Methods: A literature review on the different therapies/products currently used for chronic wounds and pathological scars was conducted. Several databases-including PubMed, ScienceDirect, Web of Science, and Google Scholar-were searched to find relevant articles on this topic.
Results: Numerous products and treatment options, including several promising new technologies, are currently available. These therapies/products aim to accelerate wound healing, reduce scarring, and ultimately reach the goal of scarless tissue regeneration.
Conclusion: Currently, no gold standard therapy exists for chronic wounds and pathological scars. Existing treatments demonstrate varying levels of efficacy, and further research is required regarding their safety and molecular mechanism(s) of action.