Butyricimonas paravirosa bacteremia associated with acute terminal ileitis: Case report and literature review

Anaerobe. 2024 Dec:90:102918. doi: 10.1016/j.anaerobe.2024.102918. Epub 2024 Oct 5.

Abstract

We present the first described case of bacteremia due to Butyricimonas paravirosa, a commensal gram-negative anaerobic bacterium identified by whole-genome sequencing in an elderly patient with acute terminal ileitis, who was successfully treated with ceftriaxone and metronidazole. We reviewed eleven previous cases of infection due to other Butyricimonas spp, which can cause a range of diseases but may be treated conservatively with a short antimicrobial course in the appropriate clinical setting. Additionally, while most Butyricimonas spp are susceptible to empiric anaerobic therapy, drug resistance has been reported in some cases.

Keywords: Anaerobe; Bacteremia; Butyricimonas paravirosa; Terminal ileitis; Whole-genome sequencing.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents* / therapeutic use
  • Bacteremia* / diagnosis
  • Bacteremia* / drug therapy
  • Bacteremia* / microbiology
  • Ceftriaxone / therapeutic use
  • Female
  • Humans
  • Ileitis / diagnosis
  • Ileitis / drug therapy
  • Ileitis / microbiology
  • Metronidazole / therapeutic use
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Ceftriaxone
  • Metronidazole