Slamf7 is dispensable in mouse models of acute lung injury

ERJ Open Res. 2024 Oct 7;10(5):00345-2024. doi: 10.1183/23120541.00345-2024. eCollection 2024 Sep.

Abstract

Slamf7 is expressed by monocyte-derived macrophages recruited to the lungs during injury. Whole-body and macrophage-specific knockouts of Slamf7 had no effect on the degree of inflammation in three mouse models of acute lung injury. https://bit.ly/3KgTJg1.