Abstract
Angiolam A, a new lactone-lactam antibiotic, was isolated from the culture broth of the myxobacterium Angiococcus disciformis strain An d30. It was active against a few Gram-positive bacteria and mutant strains of Escherichia coli with increased permeability. It appears to interfere with protein synthesis.
MeSH terms
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Anti-Bacterial Agents / isolation & purification*
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Anti-Bacterial Agents / pharmacology
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Bacillus thuringiensis / metabolism
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Bacteria / drug effects
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Bacterial Proteins / biosynthesis
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Chemical Phenomena
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Chemistry
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Fermentation
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Lactams*
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Myxococcales / metabolism*
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Lactams
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angiolam A