Primary nipple melanoma in a patient with breast cancer: A diagnosis to consider

Radiol Case Rep. 2024 Sep 25;19(12):6359-6364. doi: 10.1016/j.radcr.2024.08.156. eCollection 2024 Dec.

Abstract

Melanoma in situ of the nipple is an uncommon diagnosis, with only a few reports in the literature. Due to the variety of pathologies that can affect the nipple-areola complex, the diagnosis can be challenging. In this case report we describe a patient with cosmetic bilateral breast implants who presented with eczema of the left nipple-areola complex and suspicious microcalcifications in the lower inner quadrant of the ipsilateral breast on mammography, subsequently diagnosed with nipple melanoma and concomitant ductal carcinoma in situ.

Keywords: Ductal carcinoma in situ; Melanoma in situ; Nipple-areola complex eczema; Nipple-areola complex pathologies; Paget's disease; Primary malignant melanoma of the breast; Uncommon nipple malignancy.

Publication types

  • Case Reports