Bourbon virus is a tickborne virus that can cause human disease. Cases have been reported in Kansas, Oklahoma, and Missouri, USA. We identified Bourbon virus-specific neutralizing antibodies in patients from North Carolina. Bourbon virus infections are likely more common than previously thought, highlighting the need for improved diagnostics and surveillance.
Keywords: Bourbon virus; North Carolina; United States; neutralizing antibodies; seroprevalence; surveillance; tick-borne; ticks; vector-borne infections; viruses.