Genomic Features of Newly Diagnosed Large B-cell Lymphoma with or without Subsequent Disease Progression

Cancer Res Commun. 2024 Nov 1;4(11):2947-2954. doi: 10.1158/2767-9764.CRC-24-0337.

Abstract

Genomic features of LBCL that can be detected by clinical laboratory assays may predict for resistance to first-line immunochemotherapy, as well as support the exploration of genomic features as biomarkers of response to therapies which could be offered to patients who experience disease progression.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biomarkers, Tumor / genetics
  • Disease Progression*
  • Female
  • Genomics*
  • Humans
  • Lymphoma, Large B-Cell, Diffuse* / diagnosis
  • Lymphoma, Large B-Cell, Diffuse* / genetics
  • Lymphoma, Large B-Cell, Diffuse* / pathology
  • Male
  • Middle Aged

Substances

  • Biomarkers, Tumor