British Gynaecological Cancer Society and British Menopause Society guidelines: Management of menopausal symptoms following treatment of gynaecological cancer

Post Reprod Health. 2024 Dec;30(4):256-279. doi: 10.1177/20533691241286666. Epub 2024 Oct 11.

Abstract

These guidelines have been developed jointly by the British Gynaecological Cancer Society and British Menopause Society to provide information for all healthcare professionals managing women treated for gynaecological cancer. Menopausal symptoms can have a significant impact on quality of life for women. Cancer therapies, including surgery, pelvic radiotherapy, chemotherapy and endocrine therapy, can all affect ovarian function. The benefits and risks of using hormone replacement therapy are considered by cancer type with guidance on the type of HRT and optimal time of commencement after cancer treatment. Vaginal estrogens can be very effective for improving urogenital symptoms and are safe for the majority of women, including those for whom systemic HRT is contraindicated with rare exceptions. Alternative options to HRT are reviewed including pharmacological and non-pharmacological approaches.

Keywords: Menopause; alternative therapies; gynaecological cancer; hormone replacement therapy.

Publication types

  • Practice Guideline

MeSH terms

  • Estrogen Replacement Therapy / methods
  • Female
  • Genital Neoplasms, Female* / therapy
  • Hormone Replacement Therapy / methods
  • Hot Flashes / etiology
  • Hot Flashes / therapy
  • Humans
  • Menopause*
  • Quality of Life
  • Societies, Medical
  • United Kingdom