Invasive fungal infections in patients with leukemia carry a high mortality rate, but early diagnosis has the potential to modify this natural history. A novel screening method using Aspergillus droplet-digital polymerase chain reaction in exhaled breath condensate may have a similar performance to serum galactomannan screening. Larger studies, including other molds, are necessary.
Keywords: acute leukemia; droplet-digital PCR; exhaled breath condensate; invasive mold infections; invasive pulmonary aspergillosis.
© The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America.