Pleomorphic adenoma: Indeed, a versatile tumor

J Cancer Res Ther. 2024 Jul 1;20(5):1611-1614. doi: 10.4103/jcrt.jcrt_2259_22. Epub 2023 May 3.

Abstract

Pleomorphic adenoma is the most common and well-studied salivary gland neoplasm. It is a benign tumor most commonly occurring in the parotid gland although it can be seen in other major and minor salivary glands. There is a variety of metaplasia seen in Pleomorphic adenoma most commonly squamous metaplasia, others noted are osseous metaplasia, oncocytic metaplasia, sebaceous metaplasia, and adipocytic metaplasia. Also, at times tyrosine crystalloids are seen. This study discusses a few of the metaplasia and the presence of tyrosine crystals in pleomorphic adenoma. Indeed, this tumor proves true to its name.

MeSH terms

  • Adenoma, Pleomorphic* / diagnosis
  • Adenoma, Pleomorphic* / pathology
  • Humans
  • Metaplasia / pathology
  • Salivary Gland Neoplasms* / diagnosis
  • Salivary Gland Neoplasms* / pathology
  • Tyrosine / metabolism

Substances

  • Tyrosine