Bacillus australimaris protect Gloriosa superba L. against Alternaria alternata infestation

World J Microbiol Biotechnol. 2024 Oct 18;40(11):354. doi: 10.1007/s11274-024-04156-y.

Abstract

Gloriosa superba L., a medicinally important plant, is often affected by leaf blight disease caused by Alternaria alternata, which compromises its productivity. This study explores the protective effects of Bacillus australimaris endophyte (NBRI GS34), demonstrating that its inoculation not only inhibits the disease but also promotes plant growth and increases the concentrations of bioactive metabolites. Co-culturing NBRI GS34 with A. alternata significantly boosts protease (30-50%) and chitinase (6-28%) activities, evidencing a synergistic interaction. Scanning electron microscopy and GC-MS analysis confirm NBRI GS34's antagonistic action and reveal antifungal compounds like undecanoic acid and benzene carboxylic acid in treatments. Greenhouse experiments show a 78% reduction in disease incidence with NBRI GS34 treatment, enhancing vegetative growth and upregulating defense-related genes. Additionally, HPLC analysis reveals increased gloriosine and colchicine concentrations by 52% and 33%, respectively. These findings suggest NBRI GS34 could serve as a sustainable fungicide alternative, enhancing the production of medically valuable compounds and highlighting its potential pharmaceutical applications.

Keywords: A. alternata; G. superba; Biological control; Endophyte; Leaf blight; Plant growth promotion.

MeSH terms

  • Alternaria* / drug effects
  • Alternaria* / growth & development
  • Antifungal Agents / metabolism
  • Antifungal Agents / pharmacology
  • Ascomycota / drug effects
  • Ascomycota / metabolism
  • Bacillus* / metabolism
  • Chitinases / metabolism
  • Endophytes* / metabolism
  • Endophytes* / physiology
  • Fungicides, Industrial / pharmacology
  • Peptide Hydrolases / metabolism
  • Plant Diseases* / microbiology
  • Plant Diseases* / prevention & control
  • Plant Leaves / microbiology

Substances

  • Chitinases
  • Peptide Hydrolases
  • Antifungal Agents
  • Fungicides, Industrial

Supplementary concepts

  • Alternaria alternata

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