Identification of the Novel HLA-DQB1*03:01:01:69 Allele in a Candidate Bone Marrow Donor by Next Generation Sequencing

HLA. 2024 Oct;104(4):e15741. doi: 10.1111/tan.15741.

Authors

Diamanto Kouniaki¹, Alexandra Tsirogianni¹

Affiliation

¹ Immunology and Histocompatibility Department, Evangelismos General Hospital, Athens, Greece.

PMID: 39435990
DOI: 10.1111/tan.15741

Abstract

The HLA-DQB1*03:01:01:69 allele differs from HLA-DQB1*03:01:01:03 by a single nucleotide substitution in intron 2.

Keywords: HLA‐DQB1*03:01:01:69 novel allele; Illumina; next‐generation sequencing.

© 2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles*
Base Sequence
Exons
HLA-DQ beta-Chains* / genetics
High-Throughput Nucleotide Sequencing*
Histocompatibility Testing
Humans
Introns*
Polymorphism, Single Nucleotide
Sequence Analysis, DNA / methods
Tissue Donors*

Substances

HLA-DQ beta-Chains
HLA-DQB1 antigen