Topical Timolol for Treatment of Spider Angiomas in Children: A Case Series

Pediatr Dermatol. 2024 Oct 22. doi: 10.1111/pde.15788. Online ahead of print.

Abstract

We report five cases of spider angiomas in children treated topically with timolol 0.5% (ophthalmic solution or gel-forming solution), for 6 months. Parents and patients were advised to apply one drop twice daily. Four of them showed either partial (2) or complete response (2) and only one patient had no clinical change. No adverse effects were reported. This pilot case series shows that topical timolol may prove useful as a noninvasive, available and well-tolerated treatment option for spider angiomas in children who seek a treatment alternative to pulsed dye laser.

Keywords: adrenergic beta‐antagonists; pediatrics; telangiectasis; timolol; vascular malformations.